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1 Finally, some Excel shortcuts are just plain different on a Mac For example, the shortcut for Edit Cell in Windows is F2, and on a Mac, it's Control U The shortcut to toggle absolute and relative references is F4 in Windows, while on a Mac, its Command T For a complete list of Windows and Mac shortcuts, see our sidebyside list Change the default function key behavior If you want to change the top row of keys to work as standard function keys without holding the Fn key, follow these steps Choose Apple menu > System Preferences Click Keyboard Select "Use F1, F2, etc keys as standard function keys" If you don't see 'Use F1, F2, etc keys as standard function keys' Mac f4